Iron sequestration by macrophages decreases the potential for extracellular hydroxyl radical formation.
Alveolar macrophages (AM) from smokers contain a much higher quantity of intracellular iron than AM from nonsmokers. Since some forms of iron will catalyze the formation of hydroxyl radical (.OH) from superoxide and hydrogen peroxide, the ability of AM derived from smokers and nonsmokers to generate...
Guardado en:
| Publicado en: | J Clin Invest |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Clinical Investigation
1993
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288041/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8383703/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116310 |
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