Iron sequestration by macrophages decreases the potential for extracellular hydroxyl radical formation.

Alveolar macrophages (AM) from smokers contain a much higher quantity of intracellular iron than AM from nonsmokers. Since some forms of iron will catalyze the formation of hydroxyl radical (.OH) from superoxide and hydrogen peroxide, the ability of AM derived from smokers and nonsmokers to generate...

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Pubblicato in:	J Clin Invest
Autori principali:	Olakanmi, O, McGowan, S E, Hayek, M B, Britigan, B E
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Clinical Investigation 1993
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC288041/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8383703/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116310
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