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HIV-1 evolution: frustrating therapies, but disclosing molecular mechanisms

Replication of HIV-1 under selective pressure frequently results in the evolution of virus variants that replicate more efficiently under the applied conditions. For example, in patients on antiretroviral therapy, such evolution can result in variants that are resistant to the HIV-1 inhibitors, thus...

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Detalhes bibliográficos
Main Authors: Das, Atze T., Berkhout, Ben
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880118/
https://ncbi.nlm.nih.gov/pubmed/20478891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2010.0072
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