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HIV-1 evolution: frustrating therapies, but disclosing molecular mechanisms

Replication of HIV-1 under selective pressure frequently results in the evolution of virus variants that replicate more efficiently under the applied conditions. For example, in patients on antiretroviral therapy, such evolution can result in variants that are resistant to the HIV-1 inhibitors, thus...

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Autori principali: Das, Atze T., Berkhout, Ben
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Royal Society 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880118/
https://ncbi.nlm.nih.gov/pubmed/20478891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2010.0072
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