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HIV-1 evolution: frustrating therapies, but disclosing molecular mechanisms

Replication of HIV-1 under selective pressure frequently results in the evolution of virus variants that replicate more efficiently under the applied conditions. For example, in patients on antiretroviral therapy, such evolution can result in variants that are resistant to the HIV-1 inhibitors, thus...

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Bibliografische gegevens
Hoofdauteurs: Das, Atze T., Berkhout, Ben
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Royal Society 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880118/
https://ncbi.nlm.nih.gov/pubmed/20478891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2010.0072
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