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HIV-1 evolution: frustrating therapies, but disclosing molecular mechanisms

Replication of HIV-1 under selective pressure frequently results in the evolution of virus variants that replicate more efficiently under the applied conditions. For example, in patients on antiretroviral therapy, such evolution can result in variants that are resistant to the HIV-1 inhibitors, thus...

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Détails bibliographiques
Auteurs principaux: Das, Atze T., Berkhout, Ben
Format: Artigo
Langue:Inglês
Publié: The Royal Society 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880118/
https://ncbi.nlm.nih.gov/pubmed/20478891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2010.0072
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