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Methods of modelling viral disease dynamics across the within- and between-host scales: the impact of virus dose on host population immunity

We study the epidemiology of a viral disease with dose-dependent replication and transmission by nesting a differential-equation model of the within-host viral dynamics inside a between-host epidemiological model. We use two complementary approaches for nesting the models: an agent-based (AB) simula...

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Hlavní autoři: Steinmeyer, Shelby H., Wilke, Claus O., Pepin, Kim M.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Royal Society 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880116/
https://ncbi.nlm.nih.gov/pubmed/20478888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2010.0065
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