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A Comparison of Whole Genome Gene Expression Profiles of HepaRG Cells and HepG2 Cells to Primary Human Hepatocytes and Human Liver Tissues

HepaRG cells, derived from a female hepatocarcinoma patient, are capable of differentiating into biliary epithelial cells and hepatocytes. More importantly, differentiated HepaRG cells are able to maintain activities of many xenobiotic-metabolizing enzymes, and expression of the metabolizing enzyme...

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Autors principals: Hart, Steven N., Li, Ye, Nakamoto, Kaori, Subileau, Eva-anne, Steen, David, Zhong, Xiao-bo
Format: Artigo
Idioma:Inglês
Publicat: The American Society for Pharmacology and Experimental Therapeutics 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879958/
https://ncbi.nlm.nih.gov/pubmed/20228232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.109.031831
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