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Transmembrane Segment Five Serines of the D4 Dopamine Receptor Uniquely Influence the Interactions of Dopamine, Norepinephrine, and Ro10-4548
Conserved serines of transmembrane segment (TM) five (TM5) are critical for the interactions of endogenous catecholamines with α(1)- and α(2)-adrenergic, β(2)-adrenergic, and D1, D2, and D3 dopamine receptors. The unique high-affinity interaction of the D4 dopamine receptor subtype with both norepin...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2879936/ https://ncbi.nlm.nih.gov/pubmed/20215412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.109.164962 |
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