FGF5 as an oncogenic factor in human glioblastoma multiforme: autocrine and paracrine activities

Fibroblast growth factor 5 (FGF5) is widely expressed in embryonic but scarcely in adult tissues. Here we report simultaneous overexpression of FGF5 and its predominant high-affinity receptor (FGFR1 IIIc) in astrocytic brain tumour specimens (N=49) and cell cultures (N=49). The levels of both ligand...

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Autori principali: Allerstorfer, S, Sonvilla, G, Fischer, H, Spiegl-Kreinecker, S, Gauglhofer, C, Setinek, U, Czech, T, Marosi, C, Buchroithner, J, Pichler, J, Silye, R, Mohr, T, Holzmann, K, Grasl-Kraupp, B, Marian, B, Grusch, M, Fischer, J, Micksche, M, Berger, W
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879862/
https://ncbi.nlm.nih.gov/pubmed/18362893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2008.61
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