Fibroblast growth factor receptor-mediated signals contribute to the malignant phenotype of non-small cell lung cancer cells: therapeutic implications and synergism with epidermal growth factor receptor inhibition

Fibroblast growth factors (FGF) and their high-affinity receptors (FGFR) represent an extensive cellular growth and survival system. Aim of this study was to evaluate the contribution of FGF/FGFR-mediated signals to the malignant growth of non-small cell lung cancer (NSCLC) and to assess their poten...

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Hauptverfasser: Fischer, Hendrik, Taylor, Ninon, Allerstorfer, Sigrid, Grusch, Michael, Sonvilla, Gudrun, Holzmann, Klaus, Setinek, Ulrike, Elbling, Leonilla, Cantonati, Heidelinde, Grasl-Kraupp, Bettina, Gauglhofer, Christine, Marian, Brigitte, Micksche, Michael, Berger, Walter
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879863/
https://ncbi.nlm.nih.gov/pubmed/18852144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0444
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