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Exaggerated emotional behavior in mice heterozygous for the sodium channel Scn8a (Na(v)1.6)
The SCN8A gene encodes the α-subunit of Na(v)1.6, a neuronal voltage-gated sodium channel. Mice homozygous for mutations in the Scn8a gene exhibit motor impairments. Recently a human family with a heterozygous protein truncation mutation in SCN8A has been described. Rather than motor impairment, neu...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2008
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2879430/ https://ncbi.nlm.nih.gov/pubmed/18363861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1601-183X.2008.00399.x |
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