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Therapeutic potential of manipulating VEGF splice isoforms in oncology

Anti-angiogenic therapies currently revolve around targeting vascular endothelial growth factor-A (VEGF-A) or its receptors. These therapies are effective to some degree, but have low response rates and poor side-effect profiles. Part of these problems is likely to be due to their lack of specificit...

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Bibliographic Details
Main Authors: Rennel, Emma S, Harper, Steven J, Bates, David O
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879319/
https://ncbi.nlm.nih.gov/pubmed/19519209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fon.09.33
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