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Heterohexameric Ring Arrangement of the Eukaryotic Proteasomal ATPases: Implications for Proteasome Structure and Assembly

The proteasome has a paramount role in eukaryotic cell regulation. It consists of a proteolytic core particle (CP) bound to one or two regulatory particles (RPs). Each RP is believed to include six different AAA+ ATPases in a heterohexameric ring that binds the CP while unfolding and translocating s...

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Bibliographische Detailangaben
Hauptverfasser: Tomko, Robert J., Funakoshi, Minoru, Schneider, Kyle, Wang, Jimin, Hochstrasser, Mark
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879271/
https://ncbi.nlm.nih.gov/pubmed/20471945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2010.02.035
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