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Multiple Assembly Chaperones Govern Biogenesis of the Proteasome Regulatory Particle Base
The central protease of eukaryotes, the 26S proteasome, has a 20S proteolytic core particle (CP) and an attached 19S regulatory particle (RP). The RP is further subdivided into lid and base subcomplexes. Little is known about RP assembly. Here we show that four conserved assembly factors govern biog...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2718848/ https://ncbi.nlm.nih.gov/pubmed/19446322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.04.061 |
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