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Multiple Assembly Chaperones Govern Biogenesis of the Proteasome Regulatory Particle Base

The central protease of eukaryotes, the 26S proteasome, has a 20S proteolytic core particle (CP) and an attached 19S regulatory particle (RP). The RP is further subdivided into lid and base subcomplexes. Little is known about RP assembly. Here we show that four conserved assembly factors govern biog...

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Hlavní autoři: Funakoshi, Minoru, Tomko, Robert J., Kobayashi, Hideki, Hochstrasser, Mark
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2718848/
https://ncbi.nlm.nih.gov/pubmed/19446322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.04.061
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