NK cells mediate reduction of GVHD by inhibiting activated, alloreactive T cells while retaining GVT effects

Natural killer (NK) cells suppress graft-versus-host disease (GVHD) without causing GVHD themselves. Our previous studies demonstrated that allogeneic T cells and NK cells traffic similarly after allogeneic bone marrow transplantation (BMT). We therefore investigated the impact of donor NK cells on...

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Detalhes bibliográficos
Main Authors: Olson, Janelle A., Leveson-Gower, Dennis B., Gill, Saar, Baker, Jeanette, Beilhack, Andreas, Negrin, Robert S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2010
Assuntos:
Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2879101/
https://ncbi.nlm.nih.gov/pubmed/20233969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-05-222190
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