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The secretases: enzymes with therapeutic potential in Alzheimer disease
The amyloid hypothesis has yielded a series of well-validated candidate drug targets with potential for the treatment of Alzheimer disease (AD). Three proteases that are involved in the processing of amyloid precursor protein—α-secretase, β-secretase and γ-secretase—are of particular interest as the...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2879045/ https://ncbi.nlm.nih.gov/pubmed/20139999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrneurol.2009.218 |
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