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Mechanism by which HLA-DR4 Regulates Sex-bias of Arthritis in humanized mice
HLA class II allele DRB1*0401 is associated with predisposition to Rheumatoid Arthritis in humans as well as collagen-induced arthritis in mice. Predominantly females develop arthritis in humans and DR4 transgenic mice; however the mechanism of sex-bias is still unknown. We have investigated the mol...
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Main Authors: | , , , , , |
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格式: | Artigo |
語言: | Inglês |
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2010
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在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878859/ https://ncbi.nlm.nih.gov/pubmed/20061120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2009.12.007 |
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