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Mechanism by which HLA-DR4 Regulates Sex-bias of Arthritis in humanized mice

HLA class II allele DRB1*0401 is associated with predisposition to Rheumatoid Arthritis in humans as well as collagen-induced arthritis in mice. Predominantly females develop arthritis in humans and DR4 transgenic mice; however the mechanism of sex-bias is still unknown. We have investigated the mol...

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Main Authors: Behrens, Marshall, Trejo, Theodore, Luthra, Harvinder, Griffiths, Marie, David, Chella S, Taneja, Veena
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878859/
https://ncbi.nlm.nih.gov/pubmed/20061120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2009.12.007
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