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Auricular chondritis in NOD.DQ8.Aβo (A(g7–/–)) transgenic mice resembles human relapsing polychondritis

Relapsing polychondritis is a multisystem autoimmune disease involving cartilage destruction but no known causative antigen. HLA-DQ8 has been associated with various autoimmune diseases in humans. To study the role of DQ8 in autoimmune diseases, we have generated transgenic mice expressing DQ8 (DQA1...

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Detalhes bibliográficos
Main Authors: Taneja, Veena, Griffiths, Marie, Behrens, Marshall, Luthra, Harvinder S., David, Chella S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC296991/
https://ncbi.nlm.nih.gov/pubmed/14679179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI200317450
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