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B cells are important as antigen presenting cells for induction of MHC-restricted arthritis in transgenic mice.
Rheumatoid arthritis and its animal model, collagen-induced arthritis, are known as a T and B cell dependent disease. To analyze the role of B cells in arthritis, we generated B cell deficient (muMT) mice carrying HLA-DQ8 as transgene, Aβo.DQ8.μmt mice. HLA-DQ8 transgenic mice (Aβo.DQ8) are suscepti...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1995074/ https://ncbi.nlm.nih.gov/pubmed/17303243 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2006.12.026 |
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