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Primary granule exocytosis in human neutrophils is regulated by Rac-dependent actin remodeling
The actin cytoskeleton regulates exocytosis in all secretory cells. In neutrophils, Rac2 GTPase has been shown to control primary (azurophilic) granule exocytosis. Here, we propose that Rac2 is required for actin cytoskeletal remodeling to promote primary granule exocytosis. Treatment of neutrophils...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878813/ https://ncbi.nlm.nih.gov/pubmed/18799653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00239.2008 |
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