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Primary granule exocytosis in human neutrophils is regulated by Rac-dependent actin remodeling

The actin cytoskeleton regulates exocytosis in all secretory cells. In neutrophils, Rac2 GTPase has been shown to control primary (azurophilic) granule exocytosis. Here, we propose that Rac2 is required for actin cytoskeletal remodeling to promote primary granule exocytosis. Treatment of neutrophils...

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Sonraí Bibleagrafaíochta
Main Authors: Mitchell, Troy, Lo, Andrea, Logan, Mike, Lacy, Paige, Eitzen, Gary
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2008
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878813/
https://ncbi.nlm.nih.gov/pubmed/18799653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00239.2008
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