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Tyrosine kinase inhibitor therapy can cure chronic myeloid leukemia without hitting leukemic stem cells
BACKGROUND: Tyrosine kinase inhibitors, such as imatinib, are not considered curative for chronic myeloid leukemia – regardless of the significant reduction of disease burden during treatment – since they do not affect the leukemic stem cells. However, the stochastic nature of hematopoiesis and rece...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Ferrata Storti Foundation
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878786/ https://ncbi.nlm.nih.gov/pubmed/20007137 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.015271 |
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