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Two Modes of Interaction of the Single-stranded DNA-binding Protein of Bacteriophage T7 with the DNA Polymerase-Thioredoxin Complex

The DNA polymerase encoded by bacteriophage T7 has low processivity. Escherichia coli thioredoxin binds to a segment of 76 residues in the thumb subdomain of the polymerase and increases the processivity. The binding of thioredoxin leads to the formation of two basic loops, loops A and B, located wi...

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Detalhes bibliográficos
Main Authors: Ghosh, Sharmistha, Hamdan, Samir M., Richardson, Charles C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878571/
https://ncbi.nlm.nih.gov/pubmed/20375019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.107656
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