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Thioredoxin suppresses microscopic hopping of T7 DNA polymerase on duplex DNA
The DNA polymerases involved in DNA replication achieve high processivity of nucleotide incorporation by forming a complex with processivity factors. A model system for replicative DNA polymerases, the bacteriophage T7 DNA polymerase (gp5), encoded by gene 5, forms a tight, 1∶1 complex with Escheric...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2836631/ https://ncbi.nlm.nih.gov/pubmed/20080681 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912664107 |
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