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Thioredoxin suppresses microscopic hopping of T7 DNA polymerase on duplex DNA

The DNA polymerases involved in DNA replication achieve high processivity of nucleotide incorporation by forming a complex with processivity factors. A model system for replicative DNA polymerases, the bacteriophage T7 DNA polymerase (gp5), encoded by gene 5, forms a tight, 1∶1 complex with Escheric...

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Bibliografiset tiedot
Päätekijät: Etson, Candice M., Hamdan, Samir M., Richardson, Charles C., van Oijen, Antoine M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2010
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Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836631/
https://ncbi.nlm.nih.gov/pubmed/20080681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912664107
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