The Metabotropic Glutamate Receptor mGlu7 Activates Phospholipase C, Translocates Munc-13-1 Protein, and Potentiates Glutamate Release at Cerebrocortical Nerve Terminals

At synaptic boutons, metabotropic glutamate receptor 7 (mGlu7 receptor) serves as an autoreceptor, inhibiting glutamate release. In this response, mGlu7 receptor triggers pertussis toxin-sensitive G protein activation, reducing presynaptic Ca(2+) influx and the subsequent depolarization evoked relea...

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Detaylı Bibliyografya
Asıl Yazarlar: Martín, Ricardo, Durroux, Thierry, Ciruela, Francisco, Torres, Magdalena, Pin, Jean-Philippe, Sánchez-Prieto, José
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2010
Konular:
Signal Transduction
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878553/
https://ncbi.nlm.nih.gov/pubmed/20375012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.080838
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