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Insulin and Insulin-like Growth Factor-1 Receptors Act as Ligand-specific Amplitude Modulators of a Common Pathway Regulating Gene Transcription

Insulin and insulin-like growth factor-1 (IGF-1) act on highly homologous receptors, yet in vivo elicit distinct effects on metabolism and growth. To investigate how the insulin and IGF-1 receptors exert specificity in their biological responses, we assessed their role in the regulation of gene expr...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Boucher, Jeremie, Tseng, Yu-Hua, Kahn, C. Ronald
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878077/
https://ncbi.nlm.nih.gov/pubmed/20360006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.118620
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