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Involvement of Histone H3 Lysine 9 (H3K9) Methyltransferase G9a in the Maintenance of HIV-1 Latency and Its Reactivation by BIX01294

Elucidating the mechanism of human immunodeficiency virus, type 1 (HIV-1) provirus transcriptional silencing in latently infected cells is crucial for understanding the pathophysiological process of HIV-1 infection. It is well established that hypoacetylation of histone proteins by histone deacetyla...

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Main Authors: Imai, Kenichi, Togami, Hiroaki, Okamoto, Takashi
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878073/
https://ncbi.nlm.nih.gov/pubmed/20335163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.103531
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