Biochemical Basis of the Interaction between Cystic Fibrosis Transmembrane Conductance Regulator and Immunoglobulin-like Repeats of Filamin

Mutations in the chloride channel cystic fibrosis transmembrane regulator (CFTR) cause cystic fibrosis, a genetic disorder characterized by defects in CFTR biosynthesis, localization to the cell surface, or activation by regulatory factors. It was discovered recently that surface localization of CFT...

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Detalhes bibliográficos
Main Authors: Smith, Laura, Page, Richard C., Xu, Zhen, Kohli, Ekta, Litman, Paul, Nix, Jay C., Ithychanda, Sujay S., Liu, Jianmin, Qin, Jun, Misra, Saurav, Liedtke, Carole M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Protein Structure and Folding
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878048/
https://ncbi.nlm.nih.gov/pubmed/20351101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.080911
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