Differential Gene Expression Downstream of Toll-like Receptors (TLRs): ROLE OF c-Src AND ACTIVATING TRANSCRIPTION FACTOR 3 (ATF3)

Interferon regulatory factors (IRFs) are crucial for transcription during innate immune responses. We have previously shown that the tyrosine kinase c-Src enhances IRF-3-dependent transcription in response to viral double-stranded RNA. In this study, we show that c-Src has distinct roles in Toll-lik...

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Bibliographische Detailangaben
Hauptverfasser: Nguyen, Thuy Thanh, Johnsen, Ingvild B., Knetter, Cathrine F., Drabløs, Finn, Fitzgerald, Katherine A., Lien, Egil, Anthonsen, Marit W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878043/
https://ncbi.nlm.nih.gov/pubmed/20351107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.068817
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