Toll-like receptor 3 associates with c-Src tyrosine kinase on endosomes to initiate antiviral signaling

Double-stranded RNA (dsRNA) is produced during the replication cycle of most viruses and triggers antiviral immune responses through Toll-like receptor 3 (TLR3). However, the molecular mechanisms and subcellular compartments associated with dsRNA-TLR3-mediated signaling are largely unknown. Here we...

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Hlavní autoři: Johnsen, Ingvild Bjellmo, Nguyen, Thuy Thanh, Ringdal, Monika, Tryggestad, Anne Merete, Bakke, Oddmund, Lien, Egil, Espevik, Terje, Anthonsen, Marit W
Médium: Artigo
Jazyk:Inglês
Vydáno: 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1523188/
https://ncbi.nlm.nih.gov/pubmed/16858407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601222
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