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Differential Gene Expression Downstream of Toll-like Receptors (TLRs): ROLE OF c-Src AND ACTIVATING TRANSCRIPTION FACTOR 3 (ATF3)
Interferon regulatory factors (IRFs) are crucial for transcription during innate immune responses. We have previously shown that the tyrosine kinase c-Src enhances IRF-3-dependent transcription in response to viral double-stranded RNA. In this study, we show that c-Src has distinct roles in Toll-lik...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878043/ https://ncbi.nlm.nih.gov/pubmed/20351107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.068817 |
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