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LVIS553 Transcriptional Regulator Specifically Recognizes Novobiocin as an Effector Molecule
In this study we aimed to identify small molecules with high affinity involved in the allosteric regulation of LVIS553, a MarR member from Lactobacillus brevis ATCC367. Using high throughput screening, novobiocin was found to specifically bind LVIS553 with a K(D) = 33.8 ± 2.9 μm consistent with a bi...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878039/ https://ncbi.nlm.nih.gov/pubmed/20308066 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.111138 |
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