Tipin-Replication Protein A Interaction Mediates Chk1 Phosphorylation by ATR in Response to Genotoxic Stress

Mammalian Timeless is a multifunctional protein that performs essential roles in the circadian clock, chromosome cohesion, DNA replication fork protection, and DNA replication/DNA damage checkpoint pathways. The human Timeless exists in a tight complex with a smaller protein called Tipin (Timeless-i...

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Detalhes bibliográficos
Main Authors: Kemp, Michael G., Akan, Zafer, Yilmaz, Seçil, Grillo, Mary, Smith-Roe, Stephanie L., Kang, Tae-Hong, Cordeiro-Stone, Marila, Kaufmann, William K., Abraham, Robert T., Sancar, Aziz, Ünsal-Kaçmaz, Keziban
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
DNA and Chromosomes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878033/
https://ncbi.nlm.nih.gov/pubmed/20233725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.110304
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