Wordt geladen...

The Human Tim/Tipin Complex Coordinates an Intra-S Checkpoint Response to UV That Slows Replication Fork Displacement

UV-induced DNA damage stalls DNA replication forks and activates the intra-S checkpoint to inhibit replicon initiation. In response to stalled replication forks, ATR phosphorylates and activates the transducer kinase Chk1 through interactions with the mediator proteins TopBP1, Claspin, and Timeless...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Ünsal-Kaçmaz, Keziban, Chastain, Paul D., Qu, Ping-Ping, Minoo, Parviz, Cordeiro-Stone, Marila, Sancar, Aziz, Kaufmann, William K.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2007
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1899931/
https://ncbi.nlm.nih.gov/pubmed/17296725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.02190-06
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!