Timeless functions independently of the Tim-Tipin complex to promote sister chromatid cohesion in normal human fibroblasts

The Timeless-Tipin complex and Claspin are mediators of the ATR-dependent activation of Chk1 in the intra-S checkpoint response to stalled DNA replication forks. Tim-Tipin and Claspin also contribute to sister chromatid cohesion (SCC) in various organisms, likely through a replication-coupled proces...

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Auteurs principaux: Smith-Roe, Stephanie L, Patel, Shivani S, Simpson, Dennis A, Zhou, Ying Chun, Rao, Shangbang, Ibrahim, Joseph G, Kaiser-Rogers, Kathleen A, Cordeiro-Stone, Marila, Kaufmann, William K
Format: Artigo
Langue:Inglês
Publié: Landes Bioscience 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127161/
https://ncbi.nlm.nih.gov/pubmed/21508667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.10.15613
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