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α-AP-2 Directs Myosin VI-dependent Endocytosis of Cystic Fibrosis Transmembrane Conductance Regulator Chloride Channels in the Intestine

The actin motor myosin VI regulates endocytosis of cystic fibrosis transmembrane conductance regulator (CFTR) in the intestine, but the endocytic adaptor linking CFTR to myosin VI is unknown. Dab2 (Disabled 2) is the binding partner for myosin VI, clathrin, and α-AP-2 and directs endocytosis of low...

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Main Authors: Collaco, Anne, Jakab, Robert, Hegan, Peter, Mooseker, Mark, Ameen, Nadia
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878018/
https://ncbi.nlm.nih.gov/pubmed/20351096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.127613
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