Matrix Metalloproteinase-3 Is Increased and Participates in Neuronal Apoptotic Signaling Downstream of Caspase-12 during Endoplasmic Reticulum Stress

Although endoplasmic reticulum (ER) stress-induced apoptosis has been associated with pathogenesis of neurodegenerative diseases, the cellular components involved have not been well delineated. The present study shows that matrix metalloproteinase (MMP)-3 plays a role in the ER stress-induced apopto...

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Autori principali: Kim, Eun-Mee, Shin, Eun-Jung, Choi, Ji Hyun, Son, Hyo Jin, Park, Il-Seon, Joh, Tong H., Hwang, Onyou
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
Soggetti:
Neurobiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2878010/
https://ncbi.nlm.nih.gov/pubmed/20368330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.093799
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