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Template Proteogenomics: Sequencing Whole Proteins Using an Imperfect Database

Database search algorithms are the primary workhorses for the identification of tandem mass spectra. However, these methods are limited to the identification of spectra for which peptides are present in the database, preventing the identification of peptides from mutated or alternatively spliced seq...

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Detalhes bibliográficos
Main Authors: Castellana, Natalie E., Pham, Victoria, Arnott, David, Lill, Jennie R., Bafna, Vineet
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877985/
https://ncbi.nlm.nih.gov/pubmed/20164058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.M900504-MCP200
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