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Beyond Edman Degradation: Automated De novo Protein Sequencing of Monoclonal Antibodies
De novo protein sequencing of monoclonal antibodies is required when the cDNA or the original cell line is not available, or when characterization of posttranslational modifications is needed to verify antibody integrity and effectiveness. We demonstrate that Comparative Shotgun Protein Sequencing (...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2891972/ https://ncbi.nlm.nih.gov/pubmed/19060866 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt1208-1336 |
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