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Shank-interacting protein–like 1 promotes tumorigenesis via PTEN inhibition in human tumor cells

Inactivation of phosphatase and tensin homolog (PTEN) is a critical step during tumorigenesis, and PTEN inactivation by genetic and epigenetic means has been well studied. There is also evidence suggesting that PTEN negative regulators (PTEN-NRs) have a role in PTEN inactivation during tumorigenesis...

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Detalhes bibliográficos
Main Authors: He, Lizhi, Ingram, Alistair, Rybak, Adrian P., Tang, Damu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877943/
https://ncbi.nlm.nih.gov/pubmed/20458142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40778
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