COMMD1 disrupts HIF-1α/β dimerization and inhibits human tumor cell invasion

The gene encoding COMM domain–containing 1 (COMMD1) is a prototypical member of the COMMD gene family that has been shown to inhibit both NF-κB– and HIF-mediated gene expression. NF-κB and HIF are transcription factors that have been shown to play a role in promoting tumor growth, survival, and inva...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: van de Sluis, Bart, Mao, Xicheng, Zhai, Yali, Groot, Arjan J., Vermeulen, Jeroen F., van der Wall, Elsken, van Diest, Paul J., Hofker, Marten H., Wijmenga, Cisca, Klomp, Leo W., Cho, Kathleen R., Fearon, Eric R., Vooijs, Marc, Burstein, Ezra
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2010
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877941/
https://ncbi.nlm.nih.gov/pubmed/20458141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40583
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller