COMMD1 disrupts HIF-1α/β dimerization and inhibits human tumor cell invasion

The gene encoding COMM domain–containing 1 (COMMD1) is a prototypical member of the COMMD gene family that has been shown to inhibit both NF-κB– and HIF-mediated gene expression. NF-κB and HIF are transcription factors that have been shown to play a role in promoting tumor growth, survival, and inva...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: van de Sluis, Bart, Mao, Xicheng, Zhai, Yali, Groot, Arjan J., Vermeulen, Jeroen F., van der Wall, Elsken, van Diest, Paul J., Hofker, Marten H., Wijmenga, Cisca, Klomp, Leo W., Cho, Kathleen R., Fearon, Eric R., Vooijs, Marc, Burstein, Ezra
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877941/
https://ncbi.nlm.nih.gov/pubmed/20458141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI40583
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados