Inhibition of pulmonary fibrosis in mice by CXCL10 requires glycosaminoglycan binding and syndecan-4

Pulmonary fibrosis is a progressive, dysregulated response to injury culminating in compromised lung function due to excess extracellular matrix production. The heparan sulfate proteoglycan syndecan-4 is important in mediating fibroblast-matrix interactions, but its role in pulmonary fibrosis has no...

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Detalhes bibliográficos
Main Authors: Jiang, Dianhua, Liang, Jiurong, Campanella, Gabriele S., Guo, Rishu, Yu, Shuang, Xie, Ting, Liu, Ningshan, Jung, Yoosun, Homer, Robert, Meltzer, Eric B., Li, Yuejuan, Tager, Andrew M., Goetinck, Paul F., Luster, Andrew D., Noble, Paul W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877927/
https://ncbi.nlm.nih.gov/pubmed/20484822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38644
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