Inhibition of pulmonary fibrosis in mice by CXCL10 requires glycosaminoglycan binding and syndecan-4

Pulmonary fibrosis is a progressive, dysregulated response to injury culminating in compromised lung function due to excess extracellular matrix production. The heparan sulfate proteoglycan syndecan-4 is important in mediating fibroblast-matrix interactions, but its role in pulmonary fibrosis has no...

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Bibliographische Detailangaben
Hauptverfasser: Jiang, Dianhua, Liang, Jiurong, Campanella, Gabriele S., Guo, Rishu, Yu, Shuang, Xie, Ting, Liu, Ningshan, Jung, Yoosun, Homer, Robert, Meltzer, Eric B., Li, Yuejuan, Tager, Andrew M., Goetinck, Paul F., Luster, Andrew D., Noble, Paul W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2010
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877927/
https://ncbi.nlm.nih.gov/pubmed/20484822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38644
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