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Kaposi's Sarcoma-associated Herpesvirus K3 and K5 Proteins Block Distinct Steps in Transendothelial Migration of Effector Memory CD4+ T cells by Targeting Different Endothelial Proteins
K3 and K5 are Kaposi's sarcoma-associated herpesvirus (KSHV)-encoded E3 ubiquitin ligases that differentially reduce surface expression of various proteins in infected cells. Here we describe their effects on human dermal microvascular endothelial cells (HDMEC), a natural target of KSHV infecti...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2877909/ https://ncbi.nlm.nih.gov/pubmed/20357254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0902938 |
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