Atherosclerotic Lesion Progression Changes Lysophosphatidic Acid Homeostasis to Favor its Accumulation

Lysophosphatidic acid (LPA) accumulates in the central atheroma of human atherosclerotic plaques and is the primary platelet-activating lipid constituent of plaques. Here, we investigated the enzymatic regulation of LPA homeostasis in atherosclerotic lesions at various stages of disease progression....

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Main Authors: Bot, Martine, Bot, Ilze, Lopez-Vales, Rubén, van de Lest, Chris H.A., Saulnier-Blache, Jean Sébastien, Helms, J. Bernd, David, Samuel, van Berkel, Theo J.C., Biessen, Erik A.L.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2010
Teme:
Regular Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877866/
https://ncbi.nlm.nih.gov/pubmed/20431029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090009
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