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Inhibitors of phosphatidylinositol-3-kinase in cancer therapy

The phosphatidylinositol-3-kinase (PI3K) signaling pathway is implicated in multiple aspects of tumorigenesis and tumor maintenance, and recent years have seen significant efforts towards developing agents to inhibit the pathway. However, the development of such agents raises issues such as what spe...

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Detalhes bibliográficos
Main Authors: Ihle, Nathan T., Powis, Garth.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877630/
https://ncbi.nlm.nih.gov/pubmed/20176047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mam.2010.02.003
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