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Inhibitors of phosphatidylinositol-3-kinase in cancer therapy

The phosphatidylinositol-3-kinase (PI3K) signaling pathway is implicated in multiple aspects of tumorigenesis and tumor maintenance, and recent years have seen significant efforts towards developing agents to inhibit the pathway. However, the development of such agents raises issues such as what spe...

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Podrobná bibliografie
Hlavní autoři: Ihle, Nathan T., Powis, Garth.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877630/
https://ncbi.nlm.nih.gov/pubmed/20176047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mam.2010.02.003
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