Phase I/II Trial of 5-Fluorouracil and a Noncytotoxic Dose Level of Suramin in Patients with Metastatic Renal Cell Carcinoma

BACKGROUND: Renal cell carcinoma (RCC) is recognized as a neoplasm resistant to chemotherapy. In vitro experiments demonstrated that suramin, at noncytotoxic doses, enhanced the activity of chemotherapy including 5-fluorouracil (5-FU) in xenograft models. PATIENTS AND METHODS: A phase I/II trial of...

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Xehetasun bibliografikoak
Egile Nagusiak: George, Saby, Dreicer, Robert, Au, Jessie J. L., Shen, Tong, Rini, Brian I., Roman, Susan, Cooney, Matthew M., Mekhail, Tarek, Elson, Paul, Wientjes, Guillaume M., Ganapathi, Ram, Bukowski, Ronald M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2877588/
https://ncbi.nlm.nih.gov/pubmed/18824429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3816/CGC.2008.n.012
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